SkinCeuticals A.G.E. Interrupter Advanced Cream 48ml

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Fine lines
Deep wrinkles
Forehead lines
Nasolabial folds
Marionette lines
Glabellar lines
Crow’s feet
Loss of firmness
Reduced elasticity
Skin laxity
Reduced visible density
Dull skin
Dry skin
Mature skin
Glycation-related ageing concerns
Clients seeking a rich anti-ageing moisturiser

Helps improve visible signs associated with glycation
Helps visibly soften fine lines
Targets multiple types of facial wrinkles
Helps improve forehead wrinkles
Helps improve nasolabial folds
Helps improve marionette lines
Helps soften glabellar lines
Helps improve crow’s feet
Supports firmer-looking skin
Helps improve visible skin density
Supports skin elasticity
Promotes a smoother skin texture
Helps improve dullness and radiance
Provides rich, long-lasting moisture
Supports dry and mature skin
Contains Proxylane technology
Contains niacinamide
Suitable for morning and evening use

Use morning and evening after cleansing and applying corrective serums.

Apply a small amount over the face, neck and décolletage. Massage gently until absorbed.

In the morning, apply after a SkinCeuticals antioxidant serum and before broad-spectrum SPF50+ sunscreen.

When using retinol in the evening, apply the retinol treatment first and follow with A.G.E. Interrupter Advanced.

Suggested Routine

AM: Cleanser → C E Ferulic or Phloretin CF → P-TIOX → A.G.E. Interrupter Advanced → SPF50+

PM: Cleanser → Collagen III Amplifier → A.G.E. Interrupter Advanced

With Retinol: Cleanser → Retinol Treatment → A.G.E. Interrupter Advanced

18% Concentrated Proxylane Technology

A high-concentration technology containing Hydroxypropyl Tetrahydropyrantriol that helps support the skin’s structural matrix, firmness, density, hydration and visible correction of glycation-related ageing.

Wild-Fruit Flavonoid Blend

A combination of blueberry and pomegranate extracts that provides antioxidant support and helps address dullness and visible signs associated with glycation.

Glycyrrhetinic Acid

A liquorice-derived active that provides soothing and complementary radiance-supporting benefits.

Niacinamide

Supports the moisture barrier, visible brightness, skin resilience and more even-looking tone.

HEPES

A buffering ingredient that provides gentle surface-renewal support and helps promote smoother-looking skin.

Panthenol

A form of provitamin B5 that helps soothe, hydrate and condition the skin.

Shea Butter

A rich emollient that helps replenish moisture and soften dry or depleted skin.

Adenosine

Provides conditioning and complementary line-smoothing support.

Complete Australian Ingredient List

Aqua / Water, Hydroxypropyl Tetrahydropyrantriol, Glycerin, Propylene Glycol, Stearic Acid, Butyrospermum Parkii Butter / Shea Butter, Hydroxyethylpiperazine Ethane Sulfonic Acid, Palmitic Acid, Pentylene Glycol, Oleyl Alcohol, Arachidyl Alcohol, Myristyl Myristate, Panthenol, Niacinamide, Dimethicone, Isononyl Isononanoate, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, Glyceryl Stearate, Candelilla Cera / Candelilla Wax, Behenyl Alcohol, PEG-100 Stearate, Sodium Polyacrylate, Pentaerythrityl Tetraisostearate, 4-T-Butylcyclohexanol, Arachidyl Glucoside, Caprylyl Glycol, Xanthan Gum, Chlorphenesin, Myristic Acid, Caprylic/Capric Triglyceride, Glycyrrhetinic Acid, Parfum / Fragrance, Sorbitol, Vaccinium Myrtillus Fruit Extract, Potassium Hydroxide, Adenosine, Citric Acid, Punica Granatum Fruit Extract, Limonene, Coumarin, Linalool, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate.

Ingredient lists may change. Refer to the ingredient list printed on the product packaging for the most current information.

Clinical Information

In a 12-week, single-centre clinical study, 77 women aged 35–75 with Fitzpatrick skin types I–VI applied A.G.E. Interrupter Advanced twice daily to the face, neck and chest alongside sunscreen.

After 12 weeks, manufacturer-reported results included:

14% reduction in global fine lines
11.5% reduction in forehead wrinkles
11% reduction in nasolabial folds
7% reduction in marionette lines
7% reduction in glabellar wrinkles
7% reduction in crow’s feet

SkinCeuticals also reports:

38% reduction in visible signs linked to collagen damage
30% increase in skin density

These results relate to the finished cosmetic formulation and its visible and instrumental effects; the product should not be described as replacing lost collagen or physically lifting facial tissue.


Perfect Pairing

For advanced age management:

C E Ferulic → P-TIOX → A.G.E. Interrupter Advanced → SPF50+

For visible collagen-loss concerns:

Collagen III Amplifier → A.G.E. Interrupter Advanced

For dry, mature skin:

H.A. Intensifier Multi-Glycan → A.G.E. Interrupter Advanced

With retinol:

Retinol Treatment → A.G.E. Interrupter Advanced