SkinCeuticals Advanced RGN-6 Skin Repair Cream 50ml

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Visible redness
Post-blemish marks
Dark spots
Uneven skin tone
Fine lines and wrinkles
Loss of firmness
Rough or uneven texture
Enlarged-looking pores
Dehydrated skin
Weakened moisture barrier
Sensitive skin
Environmentally stressed skin
Mature skin
Professionally guided post-laser recovery
Clients seeking a lightweight anti-ageing moisturiser

Supports visible skin rejuvenation
Helps reinforce and repair the moisture barrier
Reduces the appearance of visible redness
Helps fade post-blemish marks
Improves the appearance of dark spots
Visibly softens wrinkles
Supports firmer-looking skin
Improves visible smoothness
Helps refine the appearance of pores
Provides comforting daily hydration
Helps soothe post-treatment discomfort
Supports recovery following laser procedures
Lightweight, non-greasy texture
Fragrance-free
Suitable for all skin types, including sensitive skin
Physician-tested to complement laser resurfacing procedures

Use once or twice daily after cleansing and treatment serums.

Dispense one to two pumps into the palm of the hand. Press the product onto the forehead, cheeks and chin, then gently blend over the face, neck and décolletage.

When using in the morning, apply after a SkinCeuticals antioxidant or corrective serum and before broad-spectrum sunscreen.

Following laser or another professional procedure, use only as directed by the treating clinician and only once the skin is suitable for topical skincare.

Suggested Routine

AM: Cleanser → C E Ferulic or P-TIOX → Advanced RGN-6 → Broad-Spectrum SPF50+

PM: Cleanser → Hydrating B5 Gel or Corrective Serum → Advanced RGN-6

Post-Treatment: Gentle Cleanser → Practitioner-Approved Serum → Advanced RGN-6 → Practitioner-Approved Sunscreen

10% Glyco-Repair™

A nutrient-rich derivative of Carob Seed Extract that helps initiate barrier repair and improve the appearance of skin texture.

1% Eperuline

Derived from Eperua Falcata Bark, Eperuline helps soothe the skin, reduce visible redness and defend against oxidative stress associated with laser procedures.

2% Niacinamide

Vitamin B3 supports the moisture barrier and helps improve visible discolouration, uneven tone and overall skin resilience.

3% Acetyl Tetrapeptide-9

A signal peptide that supports skin structure and integrity, helping promote firmer and more resilient-looking skin.

0.2% Ectoin

A protective amino acid derivative that helps defend against oxidative stress and visible discolouration while supporting skin comfort.

0.2% Bioceramide 603

A patented ceramide analogue designed to target visible discolouration and post-treatment redness.

Squalane + Shea Butter

Conditioning emollients that help soften the skin and support moisture-barrier comfort.

Complete Ingredient List

Aqua / Water / Eau, Glycerin, Ethyl Oleate, Niacinamide, Squalane, C12-16 Alcohols, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter / Shea Butter, Maltodextrin, Ammonium Polyacryloyldimethyl Taurate, Phenoxyethanol, Dimethicone, Palmitic Acid, Hydrogenated Lecithin, Cetyl Alcohol, Ceratonia Siliqua Seed Extract / Carob Seed Extract, Caprylyl Glycol, 2-Oleamido-1,3-Octadecanediol, Ectoin, Tocopherol, Eperua Falcata Bark Extract, Xanthan Gum, Ethylhexylglycerin, Phytic Acid, Adenosine, Sodium Hydroxide, Sodium Benzoate, Acetyl Tetrapeptide-9, Citric Acid.

Ingredient formulations may change. Refer to the product packaging for the most current ingredient list.

Clinical Information

In a 12-week clinical study, Advanced RGN-6 produced the following visible improvements:

69% reduction in visible redness
36% reduction in post-acne marks
26% reduction in dark spots
18% reduction in wrinkles
35% increase in visible smoothness
35% increase in visible firmness

Advanced RGN-6 was also physician-tested alongside laser procedures across all skin tones. SkinCeuticals reports that it helps reduce post-procedure downtime, with skin appearing less rough, smoother and more hydrated.

The formula was developed in collaboration with nearly 20 skin-regeneration scientists over five years, generating more than 1,000 data points supporting its six-active rejuvenation complex. The technology is supported by three patents relating to barrier repair, visible pigmentation and post-treatment redness.


Perfect Pairing

For daily antioxidant and age support:

C E Ferulic → Advanced RGN-6 → Broad-Spectrum SPF50+

For visible expression lines and firmness:

P-TIOX → Advanced RGN-6 → Broad-Spectrum SPF50+

For dehydration and barrier recovery:

Hydrating B5 Gel → Advanced RGN-6

For evening retinol support:

Retinol 0.5 or Retinol 1.0 → Advanced RGN-6

Introduce retinol gradually and use only on non-procedure nights unless professionally advised.